probenerИзвестия высших учебных заведений. ПРОБЛЕМЫ ЭНЕРГЕТИКИPower engineering: research, equipment, technology1998-99032658-5456Kazan State Power Engineering University10.30724/1998-9903-2023-25-3-3-11probener-2690Research ArticleМЕТОДЫ И ПРИБОРЫ КОНТРОЛЯ И ДИАГНОСТИКИ МАТЕРИАЛОВ, ИЗДЕЛИЙ, ВЕЩЕСТВ И ПРИРОДНОЙ СРЕДЫMETHODS AND DEVICES FOR CONTROLLING AND DIAGNOSING MATERIALS, ARTICLES, SUBSTANCES AND NATURAL ENVIRONMENTВысокодобротный ЯКР сенсор для медицинских приложенийHigh-Q litz wire NQR sensor for medical applicationsХуснутдиновР. Р.KhusnutdinovR. R.

Казань

Rustem R. Khusnutdinov

Kazan

khrr@yandex.ruМозжухинГ. В.MozzhukhinG. V.

Гебзе

Georgy V. Mozzhukhin

Gebze

ХуснутдиноваН. Р.KhusnutdinovaN. R.

Казань

Санкт-Петербург

Naira R. Khusnutdinova

Kazan

Saint Petersburg

СалахутдиновБ. М.SalakhutdinovB. M.

Казань

Bulat M. Salakhutdinov

Kazan

Казанский государственный энергетический университетРоссияKazan State Power Engineering UniversityRussian FederationТехнический университет ГебзеТурцияGebze Institute of TechnologyTurkeyКазанский государственный энергетический университет; Санкт-Петербургский государственный университетРоссияKazan State Power Engineering University; St Petersburg UniversityRussian Federation202321082023253311Copyright © Хуснутдинов Р.Р., Мозжухин Г.В., Хуснутдинова Н.Р., Салахутдинов Б.М., 20232023Хуснутдинов Р.Р., Мозжухин Г.В., Хуснутдинова Н.Р., Салахутдинов Б.М.Khusnutdinov R.R., Mozzhukhin G.V., Khusnutdinova N.R., Salakhutdinov B.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.energyret.ru/jour/article/view/2690

АКТУАЛЬНОСТЬ. Проектирование и разработка радиочастотных (РЧ) датчиков катушек является важной инженерно-технической и, одновременно, фундаментальной задачей для тех радиоспектроскопических приборов, в которых требуется увеличение чувствительности, измеряемое как отношение сигнал/шум (SNR). Радиоспектроскопия ядерного квадрупольного резонанса (ЯКР), особенно в соединениях азота, в которых резонансная частота очень низка и составляет от единицы мегагерц или ниже - до сотен килогерц, требует применения специальных решений для увеличения чувствительности. ЦЕЛЬ. Теоретическое обоснование и поиск технического решения, которое позволяет добиться высокой чувствительности на стандартном оборудовании за счет применения высокодобротного датчика. МЕТОДЫ. Рассмотрены методы оптимизации конструкции датчиков для ЯКР/ЯМР спектрометров. Рассчитана, спроектирована конструкция сенсора для спектрометра ЯКР, содержащая катушку индуктивности, намотанную проводом типа литцендрат. РЕЗУЛЬТАТЫ. Изготовлена высокодобротная катушка для датчика спектрометра, дающая увеличение добротности примерно в 1,5 раза. Использование спектрометра с данной катушкой позволило уверенно регистрировать, слабые зашумленные сигналы парацетамола при низком коэффициенте заполнения. Чувствительность датчика позволило различить по спектральным характеристикам препараты разных производителей. ВЫВОДЫ. Разработан, смоделирован и изготовлен соленоидный датчик, обладающий высокой добротностью и позволяющий регистрировать сигналы квадрупольного резонанса лекарственных средств (парацетамол) неразрушающим методом непосредственно через упаковку. Показана возможность использования такого датчика для контроля качества лекарственных средств, выявления фальсифицированных и поддельных лекарств.

RELEVANCE. The design and development of radio frequency (RF) coil sensors is an important engineering and, at the same time, fundamental task for those radio spectroscopic instruments that require an increase in sensitivity, measured as a signal-to-noise ratio (SNR). Radio spectroscopy of nuclear quadrupole resonance (NQR), especially in nitrogen compounds, in which the resonant frequency is very low and ranges from a few megahertz or lower to hundreds of kilohertz, requires the use of special solutions to increase the sensitivity. PURPOSE. Theoretical substantiation and search for a technical solution that allows achieving high sensitivity on standard equipment through the use of a high-quality sensor. METHODS. Methods for optimizing the design of sensors for NQR/NMR spectrometers are considered. The design of the sensor for the NQR spectrometer, which contains an inductance coil wound with a Litz wire, has been calculated and designed. RESULTS. A high-quality coil for the spectrometer sensor was made, which gives an increase in the quality factor by about 1.5 times. The use of a spectrometer with this coil made it possible to confidently record weak noisy signals of paracetamol at a low duty cycle. The sensitivity of the sensor made it possible to distinguish preparations from different manufacturers by their spectral characteristics. CONCLUSIONS. A solenoid sensor has been developed, modeled and manufactured, which has a high quality factor and allows recording quadrupole resonance signals of drugs (paracetamol) by a non-destructive method directly through the package. The possibility of using such a sensor for quality control of medicines, detection of falsified and counterfeit medicines is shown.

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The authors declare that there are no conflicts of interest present.